Here are the sites I've got the opportunity to work on, ranging from variety of niches and industries, each with its own unique layout, graphics, structure, color scheme, and many other design properties.
Unlike most platforms, Webflow gives complete control over the website design customization down to every pixel, and requires more technical work. Even though Webflow provides themes, you can still customize them without hitting design limitations or even start from complete scratch. It has superior design functionality compared to Shopify, but less integrated non-design functionalities, so you'll have to use third-party software.
A great eCommerce platform especially if you don't have technical skills, and want something that is very simple to use and integrates a lot of functionalities in one place. Shopify has a great selection of themes, but if you want a highly custom design, you're gonna be limited by the fixed structure of Shopify themes.